Business incubation has been globally recognized as an important tool for economic development and job creation. Normally Technology Business Incubators primarily operates in and around academic and technical institutions to tap potential technology ideas and innovations for venture creation by effectively utilizing expertise and existing infrastructure already available with the host institution. Technology based new enterprises are typically characterized as high risk and high growth ventures, and as such, they require an enabling environment like TBI to enhance the prospects of success. It is important that the money, so-called “patient money”, should also be allocated to support start-up and developing companies that are working within the framework of a living lab, until such time that the activity becomes stabilized and ensures sustainable revenue levels. Sustainability of every TBI/Living lab depends on following factors